Further properties of multiple forms of mitochondrial monoamine oxidase
نویسندگان
چکیده
منابع مشابه
Multiple Forms of Rat Liver Monoamine Oxidase
1. Treatment of a partly purified preparation of rat liver monoamine oxidase with the chaotropic agent sodium perchlorate caused the enzyme to migrate as a single band of activity on polyacrylamide-gel electrophoresis, whereas the untreated enzyme separated into a number of bands. 2. Treatment with the chaotropic agent caused no loss ofenzyme activity towards benzylamine, dopamine or tyramine. ...
متن کاملMitochondrial Monoamine Oxidase
Inhibitions of the relatively highly purified flavoenzyme, bovine kidney mitochondrial monoamine oxidase, previously described in Paper I (Erwin, V. G., and Hellerman, L., J. Biol. Gem., 242, 4230 (1967)), by several agents of current interest have been investigated. The inhibitors include Nmethyl-N-(Z-propynyl)benzylamine (pargyline), (+)-fransphenylcyclopropylamine (d form of tranylcypromine)...
متن کاملMitochondrial Monoamine Oxidase
Monoamine oxidase of bovine kidney mitochondria has been purified to high specific activity by solubilization with digitonin, ammonium sulfate fractionation, and calcium phosphate gel-cellulose column chromatography. Absorption and fluorescence spectra indicated strongly that mitochondrial monoamine oxidase is a flavoenzyme. Under anaerobic conditions, benzylamine reduced the flavin at 460 rnp ...
متن کاملStudies on monoamine oxidase. (Report XXV). Effects of alcohols on beef liver mitochondrial monoamine oxidase.
The effects of alcohols on MAO activity in beef and rat liver mitochondria were studied. MAO activity was determined manometrically using tyramine (1× 10-2 M) as substrate and expressed as O2 uptake in 60 min. At concentrations of 0.1 to 10%, methanol and ethanol increased MAO activity in both beef and rat liver mitochondria. Activation of MAO by ethanol was reversib...
متن کاملInhibition of monoamine oxidase by stilbenes from Rheum palmatum
Seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of Rheum palmatem. Their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-O-β-D-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). Anti-monoamine oxidase (MAO) activities of compounds 1–8 were tested. Compounds 1 and 8 showed sig...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1969
ISSN: 0306-3283
DOI: 10.1042/bj1140080pa